Whether you have one pimple or many blemishes, it’s ACNE! The mildest form of inflammatory acne is the papule, which appears on the skin as a small, tender firm pink bump. Pustules are small round lesions; they are inflamed and contain visible pus. Nodules are large and usually very painful, inflamed, pus-filled lesions lodged deep within the skin. They may persist for weeks or months, their contents hardening into a deep cyst. Can you get rid of acne? Yes! Be persistent. Medicine that sits on a shelve does not work!